EKKO – The first CD Microplate Reader

Applications: Spectroscopy
  • CD High Throughput Screening
  • 185-880 nm
  • 96 wells reading < 2 minutes
  • Thousands of ee values per hour
  • Noise floor : as low as 0,05 mdeg (1s)
  • Extra low operation costs
  • ¼ footprint of a conventional CD with autosampler attachment
  • 10 to 100 x faster than HPLC or conventional CD
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    The only CD Microplate Reader on the market.

    CD well plate reader for High Throughput Screening

    The EKKO™ CD microplate reader is the first well plate reader designed for circular dichroism measurements. It introduces a new fast and economic tool to meet today’s advanced pharmacopeia requirements. The EKKO™  operates like other well plate readers already on the market for absorbance and fluorescence. By eliminating the need to transfer samples to a cuvette, users significantly reduce the amount of time spent running large numbers of samples. The EKKO™ reads 96 well plates standard,  and can accommodate 384 well plates as an option. The EKKO™can read 96 wells in less than two minutes. Thousands of measurements are possible per day, making circular dichroism a new high throughput and cost saving technique.

    The EKKO™ also saves lab space with a footprint one fourth of conventional CD instruments with autosamplers.

     

    Enantiomeric Excess (ee) measurements

    The EKKO™ fills the need for high throughput screening in asymmetric synthesis to get enantiomeric excess values (ee) rapidly. Parallel synthesis is performed in the microplate. Enantiomeric excess can then be determined directly in the microplate without transferring solutions to another system. It offers an effective alternative to HPLC with no need to separate enantiomers, and by avoiding elution of solvent. Ten to one hundred times higher throughput is reasonable to expect from EKKO™ compared to alternative instruments and conventional CD instruments. It is the perfect tool to find and qualify enantiomerically enriched compounds rapidly.

    EKKO™ can measure spectra from far UV, enabling high throughput screening of protein structures, and development of biotherapeutics. The EKKO™​ is also suited for late stage research and QA/QC labs requiring high throughput.

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